The Complex Relationship Between CBD and Diabetes Worth Understanding

11 min read

Oh! I know how potpourri of savory dishes in front of your eyes can tickle your nose— and all you could do is— just watch them getting gulped by your family and friends.

*My heart sobs and my tongue too (drooling actually)* ;(

Yeah— it’s hard to be diabetic. You need discipline, self-control, precautions, and a neatly-calculated life.

But all that is lost is not lost— you win something too.

The severity of diabetes on a normal human being has compelled researchers to look for alternative means to control the blood sugar level.

So far now— the traditional drugs have done well in controlling the blood sugar level in the diabatic body; however, you know that we have to pay the price for it in the form of mild to severe side-effects.

So, what’s this alternative medicine that we are talking about?

It’s CBD— which is an abbreviation for cannabidiol.

You don’t have to look for CBD farther from the local marijuana dispensary or the drugstore (if legal in your state).

You’ll readily find them over the counter— reason being— CBD has been a talk of the town for alleviating pain, stress, anxiety, and depression.

That being said— CBD is slowly gaining traction for treating diabetes— or at least letting the body function properly.

So, how true is it? Is CBD oil for diabetes really useful?

Honestly, it’s hard to conclude that CBD for diabetes makes sense in the long run because we don’t have enough evidence to support the claim.

While type 1 diabetes is an autoimmune syndrome where the immune system stops beta cells in the pancreas to produce insulin, type 2 can be caused by any reason such as your dietary habits, weight, ethnicity, etc. where insulin is barred from functioning.

Insulin is vital in the body because it pushes the sugar (glucose) from carbohydrates to the cells and lets them use it as energy.

If your body has enough energy— insulin will store glucose until you need energy for the next session.

But the claim CBD oil for diabetes is effective still needs proper scrutinization.

Let’s just assume that CBD attenuates diabetic symptoms.

So, if it does— it should be effective in retaining back the lost glory of insulin in the body— only when it allows insulin to work for which it is known. Right?

But so far— unfortunately, no clinical studies have directly shown that CBD increases the insulin level in the body.

So, if it’s clear— why are we even discussing the role of CBD in a diabetic body?

Since we don’t know the exact interaction of CBD with the metabolic system of our body— our researchers have a bit of hope with CBD oil.

Partly because of the experiments conducted on animal models and their positive results.

Let’s find out what these experiments in mice or rats suggest.

One of the experiments on rats with low blood flow documents that lack of blood supply can also cause diabetes.

When these rats with low blood influx in the brain were subjected to CBD— the empirical observation led to significant findings. [1]

  • Administration lowered down the effect of hyperglycemia.
    *Hyperglycemia is a condition where your blood has a high sugar level— an essential characterization for diabetes.*
  • Admission effectively reduced the bad cholesterol level.
    *The bodies with high sugar levels have low-density lipoprotein cholesterol, which further aggravates the diabetic condition. On the other hand, if your body contains high-density lipoprotein— it means that you have good cholesterol in the body that leads to a healthy life. Unlike fats, cholesterol can’t be exercised off— you can only regulate it with your diet.*
  • Consumption upped the insulin level.
    *As mentioned— your body needs to have insulin to convert sugar into energy. The lack of insulin won’t allow your body to convert these glucose molecules into energy, thereby making you feel less energetic and prone to many other diseases.*

Well, here’s what another study of CBD administration in mice has to say. [2]

  • Relieved inflammation, pain, and swelling from nerve damage.
    *Diabetes is a pain in the neck because it brings a lot of comorbid conditions, which include as serious a situation as diabetic neuropathy. Neuropathy is a condition in which your body starts destroying the nerves. As a result of the internal attack on the nerves— you suffer inflammation, pain, and swelling at different organs of the body.*
  • Brought down the risk of diabetes.
    *Again, multifactorial reasons cause diabetes Type-2. It could be anything, and it’s tough to diagnose. So, CBD injections in mice seemed to have tamed any of these causes to reduce the probability of diabetes.*
  • Leads the way for good fat.
    *Unlike cholesterol, fats can be exercised off. They both are lipids, and both have good and corrupt nature. The white fat in your body leeways the possibilities of diabetes. However, CBD can turn these white fatty lipids into brown fat— the healthy fat cells that are needed to keep the blood sugar level in check.*

The results of these two studies have generated a bit of optimism among clinical researchers; however, that doesn’t mean what stands valid for rats may hold true for humans.

Laboratory conditions, the differences in traits, and a lot of other environmental factors can change the result if CBD gets tested on humans.

So, we should wait until we reach the final verdict for it.



If not CBD, then maybe…THC?

Well, cannabis has more than 120 compounds, of which THC and CBD are the most studied molecules.

While medical scientists are researching the effects of CBD on diabetes, some of them are really intrigued about the potential benefits of the most well-known cannabinoid — THC— on the same disease.

Unlike CBD, THC is known for inducing a tripping effect that floors euphoria in front of your eyes, thereby locking you on the couch.

There’s absolutely no doubt that THC has its recreational advantages over CBD, but the matter of discussion is— does THC also have a medicinal advantage over its counterpart CBD?

Here’s one study that demonstrates the effect of marijuana on glucose, insulin, and insulin resistance. [3]

The study clearly says that marijuana can help control those factors like large waist circumference and fats, which potentiate the occurrence of diabetes.

Again, there’s no clear evidence which chemical component of marijuana led its way in fighting the problem.

It’s a call on researchers to find the impact of these 120 chemicals in marijuana and help the world reach conclusive evidence.

So, does THC have medicinal advantages over CBD? I’d say it’s tentative because of the variance in results.

Diving deeper to learn CBD interaction with diabetic bodies

As mentioned— we don’t have substantial results that prove the connection between CBD and its impact on diabetes; however, we can learn a lot with the medical speculation going around.

Here’s what we are speculating of CBD when it is given to a diabetic patient:

  • It can fend off stress…

You never know— whatever you do with your life may contribute to the dangers of diabetes.

One being— feeling stressed.

Stress is an emotion that is driven by cortisol hormones.

These hormones are known to produce glucose in the body, which pushes the ideal glucose level beyond the threshold value.

And as you know— more glucose will lead to the higher sugar level in the circulatory system, which, in turn, will magnify the chances of hyperglycemia.

We also have mounting evidence that stress is a potential contributor to diabetes. [4]

We may not have the clear idea about the relationship between CBD and diabetes, but we have inked kinship between CBD and stress.

Anecdotes have proven that CBD possesses anti-stress properties that bridle the cortisol level in the body, thereby possibly ruling out one of the causes of diabetes. [5]

So, we might not have direct information on insulin level— but we do have about glucose level.



  • It can cut down bothering-fats…

Fats like to add its “two-bit” to your diabetic condition— especially the ones cumulated right in your belly.

Consuming too many fats will mean that you are introducing more calories to the body than required, which replicate like a virus.

Yes, fatty cells are like viruses that create clones if you aren’t exercising or taking care of your physique.

There are enough documented medical papers which confirm that more body fat worsens the diabetic condition in a diabetic patient, and fancies the chances of diabetes in the ones who haven’t been diagnosed yet. [6]

However, CBD has shown massive potential in fat browning. [7]

It’s the process in which white fat cells are burned down into brown fat.

The growing numbers of brown fat cells signify that your body is losing the bad fat content, which automatically minimizes the chances of diabetes.

  • It can regulate the blood flow…

If you ask me— I’d say healthy blood flow is the root of a healthy lifestyle.

Since the seamlessness of blood flow decides whether you are getting essential minerals and proteins to the different parts of your organs— any tormentation with them can lead to several other issues— and one of them being diabetes.

In fact, many studies have linked high blood flow (hypertension) with diabetes.

As hypertension constricts the blood vessels— a lot of mechanisms alters in the body.

Some say that hypertension also causes insulin resistance.

One of the studies showed that 50% of the hypertensive respondents had diabetes. [8]

If the modification in blood flow can create an imbalance between glucose and insulin level— it gets imperative that we try to get back its routine.

CBD edibles and oils could just be the elements we are looking to erase of hypertension.

This test on respondents shows that patients with low heart rate and high blood pressure face reciprocal effects with CBD. [9]

The cannabis-element works as a vasodilator, which relaxes the muscles walls of the blood vessels, thereby allowing better blood influx through the arteries.

So, controlling hypertension may help us get rid of another factor that often leads to diabetes.

  • It can manage thyroid symptoms…

Unfortunately, even thyroid can cause diabetes.

Thyroid issues are known to interfere with the metabolic activities of the body.

Any alteration in metabolism can increase the glucose level in the body. [10]

To clear the argument— hypothyroidism, the condition in which the thyroid hormone goes below the low-normal range leads to diabetes.

Some studies also show the link between hyperthyroidism and diabetes.

However, hypothyroidism has been more active in worsening the glycemic control, specially in the prediabetic bodies.

The worst part about thyroid disorders is that they result in severe symptoms such as pain, anxiety, depression, etc. that are often known to aggravate the diabetic condition.

We can call it a double-edged-sword that needs immediate blunting to prevent diabetes escalation.

Again, taking CBD supplements won’t benefit diabetic disorder directly, but it will manage the symptoms of thyroid disorders, thereby making you less susceptible to diabetes.

Scientists say that the cells of thyroid glands have cannabinoid receptors that bind CBD, activate it, and maximize its medical sanctity in the body. [11]

There are many other ways by which CBD can control the risks of diabetes and not diabetes directly.

Glance through this quick list:

  1. If you don’t indulge in physical activities and are relatively dull— you are likely to develop diabetes. Diabetes loves to target couch potatoes. But some respondents believe that CBD, somehow, has wake-promoting properties that revitalize your body and enhance the energy level for the necessary workout. [12]
  2. If you have cardiovascular problems— they may lead to diabetes. An abnormal cardiovascular proceeding alters the way the heart behaves in your body. And the varying heart rates will change the way blood vessels perform in the body. And as mentioned— blood vessels have connections with diabetes. As CBD has a vasodilating impact on blood-vessels— its cascading effect is observed on cardiovascular performance. [13]
  3. If you are a woman, PCOS and postpartum depression can also cause diabetes. In both the conditions, high insulin levels are found in blood and not in the cells, which suggests that insulin fails to get into the cells that could convert glucose into energy. There hasn’t been an in-depth study between PCOS and CBD; however, whatever we have suggests that CBD can tame PCOS and the threats of diabetes linked with it. [14]

So, what’s the takeaway?

Well, the biggest takeaway is— you never know what’s making your sugar levels high in the blood if you are suffering from diabetes Type-2.

Only an elixir with super-natural potion powers can fight off with “any of these” multivariate features.

So far now— CBD is not the elixir— but it’s slowly progressing towards being one— because of the societal status it has earned in the past decade, and the urge to promote it as medical marijuana has gone berserk.

If you are fighting off diabetes with CBD, we recommend you use more effective ways of administration, such as lingual, sublingual, and skin application. Avoid smoking it because it’ll only worsen the condition.



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