Wall Clock9 min read
How CBD Treat Ulcerative Colitis

Have you been moaning up late at night because your abdominal cramps are unbearable, and rectal bleeding is shooting up your heart rate?

Is your digestive system burning as if it’s placed over the barbeque grill sticks?

It seems that your ulcerative colitis won’t let you make peace with your day— and mostly your night too.

For every disease, if you were asked to rate your customer experience— Ulcerative Colitis would quickly get a lot of “frustrating experience.”

Because that’s how frustrating it is.

But it’s not the end of the road.

There are plenty of immunosuppressive medicines in the market to combat such a painful problem.

While most of the drugs comply well for mellowing down the inflammation in the bowel, they also have substantial side-effects in the body.

That gives you the right to choose an alternative option that could have similar potency as any traditional drugs, and more importantly, all that with zero side effects.

If you are searching for one, medical marijuana can be the right choice for you.

It easily sweeps the number one spot as an alternative means for fending off ulcerative colitis.

Marijuana basically splits into two important kingdoms— a hash with higher CBD content and the other with high THC content.

CBD for Ulcerative Colitis

CBD is predominantly crowned as medical marijuana, whereas THC as a recreational green blade.

The studies regarding the medical proficiency of CBD and recreational characteristics of THC date long back; however, with time— we have a lot of information on these primary components.

And so far, we understand that each one of the two shows specific therapeutic effects, albeit THC gives you high and CBD negates its effect.

Several anecdotes display a medicative link between ulcerative colitis and marijuana, although we still need strong proofs to support our statements.

But before we get into the deeper impact of medical marijuana on ulcerative colitis, let’s understand what ulcerative colitis is.

Ulcerative Colitis— the what’s and the how’s

There’s a famous quote about Ulcerative Colitis.

“Every time you feel good. Colitis will knock you down.”

That’s how excruciating it is.

It’s an inflammatory disorder in the digestive tract whose symptoms range excruciating pain to weight loss, blood in the stool to leakage of stool, and a lot more.

More than bringing embarrassment, the symptom can be fearsome.

The sores in the inner lining of the large intestine (colon) and rectum can last long if not given proper medical attention.

It’s a gradual process that often aggravates steadily and doesn’t spring out as an overnight result.

It can also send you in a very weakened and infirmed state and potentially have life-threatening impacts.

The worrying part is— we don’t have a permanent cure.

The reason why it’s hard to cure permanently is that we don’t understand the real causes of it.

Removing the disease from the root needs a deeper understanding of all the causes.

However, slight changes in lifestyle and medical treatment can suppress the symptoms on a large scale.

Furthermore, the introduction of medical marijuana for ulcerative colitis has boosted the bench-strength for medical aids.

Let’s try to break down its causes as far as our current empirical studies suggest and see if medical marijuana can really take on it. 

Cause 1: Immune System Malfunction

It’s believed that the immune system malfunction/abnormal immune functionality can arrange an environment for ulcers in the digestive tract.

When viruses or bacteria invade your body, the immune system gets into the action and tries to negotiate with these foreign microbes.

While setting up a strong case for you and fighting off with these invaders, the system also attacks the cells in the digestive tract.

It leads to inflammation in the inner part of the large intestine and rectum.

The inflammatory problem may persist even after the infection is resolved— because the immune system may later never understand when to stop.

Calling it an autoimmune disease is a coherent term because your own immune system progresses towards destroying/troubling the organs in the body.

Solution 1: Boosting the immune system with CBD

Research has shown that CBD can play an influencing effect on the immune system.

The CBD-infused edibles and beverages in your refrigerator may work as a potent immunomodulator/immunosuppressive. 

CBD For Immune System

Here’s how it can prevent your immune system from destroying the digestive tract cells.

  • It works as an anti-inflammatory agent whose primary goal is to limit the inflammatory response from the immune system.
  • It disables the memory of the immune system to recognize foreign substances.
  • It regulates cytokine proteins and prevents them from producing excessive white blood cells, which are known to attack the cells— foreign or home. 

We can’t confirm that it will necessarily work because of the lack of the sample size to be observed; however, limited data decently proves its efficacy in taming the immune system’s abnormality.

Cause 2: Psychological reasons

Earlier it was believed that psychological reasons like stress had something to do with the birth of ulcers in the tract.

However, recent findings demonstrate that psychological imbalance can’t lead to such ulcers.

The medical community has clearly ruled out stress as one of the factors for blooming up the disorder.

Despite all the new learnings, studies make that stress can enhance the symptomatic flare. [1]

The comorbidity of UC and chronic stress will weaken the intestinal permeability and create more room for bacteria and viruses to translocate into the linings of the intestine.

Not only this. Stress can get you the other way as well.

Generally, a stressed body produces cortisol, which pushes your body in the fight and flight mode.

The modes also keep your adrenaline in check.

The higher adrenaline level will trigger the immune system. 

Not that they are bad, but if you have UC— the efficient action of the immune system will have a rough effect on your tracts.

And that’s how stress indirectly enhances the severity of it.

Solution 2: Becoming stress-free with CBD

Stress and depression are sometimes also caused by low-level serotonin.

CBD tries to increase this level by interacting with the cannabinoid receptors CB1 and CB2.

The receptors are nothing but protein-based chemicals in our body cells.

It’s considered that CBD’s interaction with these receptors have the same effect as what SSRIs have in amplifying the serotonin hormone.

CBD For Stress

It would need special medical instructions from your doctor whether you can use CBD for SSRI; however, there’s no doubt that CBD has been so far successful in alleviating stress.

And as mentioned, its anti-inflammatory properties already make it a great fit to calm down the overactivation of the immune system, which results in tract spasm.

Cause 3: Family history, race, and age

One of the exciting patterns noted in patients who have ulcerative colitis is that they have parental/sibling history of it.

Honestly, the ball is never in your court, and you can’t really do anything about it.

Apart from family patterns, there has been generalization with race, ethnicity, and age as well.

If you are a white person or belong to the Ashkenazi Jewish root— you are likely to develop the condition.

The condition is also prevalent in people below the age of 30.

However, that’s not some hardbound rule.

You can be its victim at 60 as well. 

Unfortunately, the symptoms can trigger even when your lifestyle is good because of the attributes you absolutely had no control whatsoever, such as race and family background.

What can CBD do about it?

We don’t have any clue regarding CBD’s competence to combat genetic diseases except Huntington’s disease. 

Although there’s no proof that early-age CBD supplementation will stave off the disease from surging while you get into your late 20s, there’s no harm in consuming it if your locality allows it.

Again, we can’t claim blatantly that CBD is an apparent medical fit for UC; however, its potent medicinal properties can give you relief against the burning sensation in the intestine.

CBD has a unique chemokine suppressing property.

Chemokine— associated with the group of cytokines is a type of informer which whistle-blows the nuisance of invaders in the body.

The immune system receives the information cited by it.

As soon as they receive the information, they reach the spot and start bombing white blood cells to get off these microbes.

That causes cell damage in the tracts as well, which results in inflammation.

CBD suppresses these groups of chemokines, thereby bridling down the action of the immune system in full flow.

CBD…Road to NSAID?

Like any other NSAID, CBD likes to fight inflammation in not just one but a number of ways.

The NSAID drug, which inhibits the inflammatory prostaglandins, has a powerful impact on ulcers in the tract, but the same drug also contributes to gastric ulcers.


Such paradoxes make NSAID contraindicated to IBD and UC.

Thankfully, CBD doesn’t have any such side-effects like NSAIDs.

So, are we heading up towards introducing CBD in the NSAID category?

Well, not yet! 

As the legalization of CBD continues to take place at the federal level, we do hope that it gains the much-deserved status.

The final verdict

CBD, no matter what, has intrigued many to go for an alternative and seek a different choice than what they have in front of their eyes for attenuating UC.

That’s the probable reason why CBD is getting spaces into the house racks— maybe each shelf has more to say than the anecdotal studies and proofs.

So don’t wait and CBDize yourself to see if it treats your condition.

As it barely has a side effect/ it’s side-effect profile is really positive— there’s no harm in trying it.

You have absolutely nothing to lose.

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